Across TCGA cell cohorts, TRIM10 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible TRIM10-associated genes across cancer lineages are TNP1, DYDC1, and NLRP8. Each is linked with TRIM10 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM10-to-partner and partner-to-TRIM10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM10→partner) and Y-score (partner→TRIM10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TNP1 →	+0.160	+4.415	<.001	.007	3	2
OESOPHAGUS	DYDC1 →	+0.146	+4.906	<.001	.006	3	1
OESOPHAGUS	NLRP8 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	KLHL34 →	+0.013	+4.906	<.001	.006	3	1
OESOPHAGUS	AADACL3 →	+0.410	+4.906	<.001	.006	3	1
OESOPHAGUS	PPIAL4F →	+0.060	+4.906	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

TRIM10 survival (RNA) · tumor vs normal (RNA) · all TRIM10 data types