Across TCGA pan-cancer cohorts, TRIM10 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of TRIM10’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where TRIM10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TRIM10 is over-expressed in tumor, although a few such as KICH and COAD show the opposite, repressed pattern.
STAD, KICH, and KIRC are the cancer types where TRIM10 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRIM10 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.