TRHR

Across TCGA cell cohorts, TRHR RNA expression is significantly associated with the go_rna of many other GO terms, with 1,269 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TRHR-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, Post-transcriptional gene silencing, and Subtelomeric heterochromatin formation. Each is linked with TRHR in more than 8 cancer types. Because this analysis shows association rather than direction, both TRHR-to-partner and partner-to-TRHR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear-transcribed mRNA catabolic process grouped by TRHR-low versus TRHR-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRHR→partner) and Y-score (partner→TRHR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Nuclear-transcribed mRNA catabolic process →	+0.027	+0.040	.001	.005	3	9
BLOOD_Lymphoma	Post-transcriptional gene silencing →	+0.056	+0.055	<.001	.005	3	8
SOFT_TISSUE	Subtelomeric heterochromatin formation →	+0.087	+0.046	<.001	.001	3	8
SKIN	Signal transduction in response to DNA damage →	+0.039	+0.033	<.001	.001	3	8
SKIN	RNA catabolic process →	+0.033	+0.028	<.001	.007	3	8
SOFT_TISSUE	RISC complex assembly →	+0.088	+0.067	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,269 associations by consensus.

Nuclear-transcribed mRNA catabolic process by TRHR expression — SKIN

Explore this box plot interactively →