Across TCGA patient cohorts, TREML3P mutation is significantly associated with the RNA expression of many other genes, with 112 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TREML3P-associated genes across cancer lineages are RNU2-50P, NPM1P28, and ARL2BPP6. Each is linked with TREML3P in more than 2 cancer types. Because this analysis shows association rather than direction, both TREML3P-to-partner and partner-to-TREML3P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TREML3P→partner) and Y-score (partner→TREML3P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU2-50P →	+0.422	+5.631	<.001	.004	3	3
BRCA	NPM1P28 →	+0.081	+5.409	<.001	.005	3	2
BRCA	ARL2BPP6 →	+0.099	+5.971	<.001	.002	3	2
LUAD	VN1R4 →	+0.073	+5.217	.001	.007	3	2
LUAD	SEPTIN14P24 →	+0.408	+5.343	<.001	.006	3	2
UCEC	RNU6-718P →	+0.188	+4.069	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 112 associations by consensus.

Exploration

TREML3P survival (RNA) · tumor vs normal (RNA) · all TREML3P data types