TRBV6-8

Across TCGA patient cohorts, TRBV6-8 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,369 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TRBV6-8-associated proteins across cancer lineages are SEPTIN1_S315, SKAP1, and PSME2. Each is linked with TRBV6-8 in more than 4 cancer types. Because this analysis shows association rather than direction, both TRBV6-8-to-partner and partner-to-TRBV6-8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRBV6-8 versus SEPTIN1_S315 in LUAD, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRBV6-8→partner) and Y-score (partner→TRBV6-8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SEPTIN1_S315 →	+0.865	+0.461	<.001	.001	3	5
CCRCC	SKAP1 →	+0.642	+0.522	<.001	.001	3	5
HNSC	PSME2 →	+0.376	+0.450	<.001	.001	3	4
CCRCC	PSTPIP1 →	+0.344	+0.404	.003	.001	3	4
CCRCC	PYHIN1 →	+0.664	+0.588	.001	.001	3	4
LSCC	CARMIL2_S1381 →	+0.938	+0.511	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,369 associations by consensus.

TRBV6-8 vs SEPTIN1_S315 — LUAD

Explore this scatter interactively →