TRBV6-7

Across TCGA patient cohorts, TRBV6-7 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,832 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TRBV6-7-associated proteins across cancer lineages are GBP4, VAV1, and COTL1. Each is linked with TRBV6-7 in more than 5 cancer types. Because this analysis shows association rather than direction, both TRBV6-7-to-partner and partner-to-TRBV6-7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRBV6-7 versus GBP4 in CCRCC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRBV6-7→partner) and Y-score (partner→TRBV6-7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	GBP4 →	+0.593	+0.453	<.001	.003	3	6
CCRCC	VAV1 →	+0.496	+0.616	<.001	<.001	3	5
LSCC	COTL1 →	+0.374	+0.359	<.001	<.001	3	5
CCRCC	LCP2 →	+0.414	+0.525	.001	<.001	3	5
LSCC	RCSD1 →	+0.527	+0.659	<.001	<.001	3	5
CCRCC	SASH3 →	+0.510	+0.610	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,832 associations by consensus.

TRBV6-7 vs GBP4 — CCRCC

Explore this scatter interactively →