TRBV6-7

Across TCGA pan-cancer cohorts, TRBV6-7 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated TRBV6-7 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher TRBV6-7 RNA is associated with better overall survival. In most high-consensus cancer types, elevated TRBV6-7 expression acts as an unfavorable survival marker, although some lineages such as BLCA and THYM show a favorable association.

BLCA, LUSC, and UCEC are the cancer types where TRBV6-7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	All	0.585	0.331	<.001	96	view →
LUSC	OS	Tertile	II,III,IV	0.485	0.659	.005	48	view →
UCEC	DFS	Tertile	All	0.840	0.913	.002	46	view →
THYM	OS	Median	All	1.000	0.726	<.001	19	view →
UCS	DFS	Tertile	All	0.190	0.483	.026	18	view →
READ	DFS	Tertile	IV	0.195	0.661	.001	18	view →
PCPG	OS	Tertile	All	0.885	0.979	.027	15	view →
DLBC	DFS	Quartile	All	0.433	0.984	.017	12	view →
SKCM	OS	Tertile	All	0.405	0.309	.006	12	view →
THCA	DFS	Median	All	0.924	0.866	.026	5	view →
STAD	DFS	Median	All	0.491	0.589	.021	3	view →
MESO	DFS	Tertile	IV	0.183	0.434	.043	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

TRBV6-7–BLCA (OS)

Open the BLCA breakdown →