Across TCGA patient cohorts, TRBV6-4 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,840 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TRBV6-4-associated proteins across cancer lineages are ANKRD44, CASP1, and GRAP2. Each is linked with TRBV6-4 in more than 6 cancer types. Because this analysis shows association rather than direction, both TRBV6-4-to-partner and partner-to-TRBV6-4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRBV6-4→partner) and Y-score (partner→TRBV6-4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ANKRD44 →	+0.325	+0.264	<.001	.001	3	7
HNSC	CASP1 →	+0.376	+0.441	.003	.002	3	5
BRCA	GRAP2 →	+0.498	+0.410	<.001	<.001	3	5
BRCA	PSMB10 →	+0.387	+0.474	<.001	<.001	3	5
HNSC	PSME2 →	+0.331	+0.321	<.001	<.001	3	5
CCRCC	THEMIS →	+0.594	+0.566	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,840 associations by consensus.

Exploration

TRBV6-4 survival (RNA) · tumor vs normal (RNA) · all TRBV6-4 data types