Across TCGA patient cohorts, TRBV5-5 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,123 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TRBV5-5-associated proteins across cancer lineages are ANKRD44, NFATC2, and ARHGAP30. Each is linked with TRBV5-5 in more than 7 cancer types. Because this analysis shows association rather than direction, both TRBV5-5-to-partner and partner-to-TRBV5-5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRBV5-5→partner) and Y-score (partner→TRBV5-5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ANKRD44 →	+0.470	+0.854	<.001	<.001	3	8
LSCC	NFATC2 →	+0.450	+0.642	<.001	<.001	3	7
HNSC	ARHGAP30 →	+0.521	+0.534	<.001	<.001	3	7
OV	ACAP1_T739 →	+0.702	+0.691	.003	.003	3	7
LSCC	WDFY4 →	+0.505	+0.620	<.001	<.001	3	7
BRCA	SEPTIN1 →	+0.870	+0.884	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,123 associations by consensus.

Exploration

TRBV5-5 survival (RNA) · tumor vs normal (RNA) · all TRBV5-5 data types