TRBV3-1

Across TCGA patient cohorts, TRBV3-1 protein abundance is significantly associated with the RNA expression of many other genes, with 270 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TRBV3-1-associated genes across cancer lineages are NME5, UBL4A, and CAMKK2. Each is linked with TRBV3-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRBV3-1-to-partner and partner-to-TRBV3-1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRBV3-1 versus NME5 in CCRCC, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRBV3-1→partner) and Y-score (partner→TRBV3-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	NME5 →	+2.237	+1.164	.007	.009	3	2
CCRCC	UBL4A →	-0.452	-0.482	.003	.002	3	1
CCRCC	CAMKK2 →	-0.448	-0.983	.003	<.001	3	1
CCRCC	ACSS3 →	+1.177	+0.928	.005	.001	3	1
CCRCC	GPD2 →	-0.416	-1.215	.003	.003	3	1
CCRCC	FHL2 →	-1.659	-1.042	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 270 associations by consensus.

TRBV3-1 vs NME5 — CCRCC

Explore this scatter interactively →