TRBV3-1

Across TCGA patient cohorts, TRBV3-1 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRBV3-1-associated genes across cancer lineages are Erythrocytes and Melanocytes. Each is linked with TRBV3-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRBV3-1-to-partner and partner-to-TRBV3-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Erythrocytes grouped by TRBV3-1-low versus TRBV3-1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRBV3-1→partner) and Y-score (partner→TRBV3-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Erythrocytes →	+0.029	+2.813	.015	.037	3	1
SKCM	Melanocytes →	+0.077	+2.839	.036	.035	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Erythrocytes by TRBV3-1 expression — SKCM

Explore this box plot interactively →