TRBV12-5

Across TCGA patient cohorts, TRBV12-5 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,216 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TRBV12-5-associated proteins across cancer lineages are ANKRD44, SEPTIN1_S206, and SH3KBP1. Each is linked with TRBV12-5 in more than 7 cancer types. Because this analysis shows association rather than direction, both TRBV12-5-to-partner and partner-to-TRBV12-5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRBV12-5 versus ANKRD44 in UCEC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRBV12-5→partner) and Y-score (partner→TRBV12-5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ANKRD44 →	+0.423	+1.093	.001	.002	3	8
HNSC	SEPTIN1_S206 →	+1.103	+0.485	<.001	<.001	3	7
UCEC	SH3KBP1 →	+0.373	+1.045	.003	.006	3	7
BRCA	MAP4K1 →	+0.525	+0.310	<.001	<.001	3	7
CCRCC	ARHGAP30 →	+0.566	+0.558	<.001	<.001	3	7
HNSC	NFATC2 →	+0.411	+0.711	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,216 associations by consensus.

TRBV12-5 vs ANKRD44 — UCEC

Explore this scatter interactively →