Across TCGA patient cohorts, TRAV9-2 mutation is significantly associated with the RNA expression of many other genes, with 179 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRAV9-2-associated genes across cancer lineages are RNU6-1228P, RN7SL248P, and FTLP18. Each is linked with TRAV9-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV9-2-to-partner and partner-to-TRAV9-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV9-2→partner) and Y-score (partner→TRAV9-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1228P →	+0.291	+4.727	<.001	.003	3	2
UCEC	RN7SL248P →	+0.118	+4.400	<.001	.006	3	1
LUAD	FTLP18 →	+0.158	+7.333	<.001	<.001	3	1
LUAD	FAM224A →	+0.021	+5.099	.001	.008	3	1
LUAD	LINC02374 →	+0.040	+6.197	.001	.001	3	1
SKCM	SETD6P1 →	+0.105	+3.343	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 179 associations by consensus.

Exploration

TRAV9-2 survival (RNA) · tumor vs normal (RNA) · all TRAV9-2 data types