Across TCGA patient cohorts, TRAV21 mutation is significantly associated with the RNA expression of many other genes, with 109 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRAV21-associated genes across cancer lineages are IGLV10-67, OOSP1P2, and COX6CP17. Each is linked with TRAV21 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV21-to-partner and partner-to-TRAV21 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV21→partner) and Y-score (partner→TRAV21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	IGLV10-67 →	+0.157	+4.433	<.001	.007	3	1
BLCA	OOSP1P2 →	+0.201	+4.435	<.001	.002	3	1
SKCM	COX6CP17 →	+0.147	+3.213	<.001	.007	3	1
SKCM	COPRSP1 →	+0.065	+2.964	<.001	.001	3	1
SKCM	RNU7-80P →	+0.246	+3.458	.001	.004	3	1
SKCM	EGFLAM-AS3 →	+0.028	+4.810	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 109 associations by consensus.

Exploration

TRAV21 survival (RNA) · tumor vs normal (RNA) · all TRAV21 data types