Across TCGA patient cohorts, TRAV16 mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRAV16-associated genes across cancer lineages are MRPS17P5, MIR6833, and MIR6817. Each is linked with TRAV16 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV16-to-partner and partner-to-TRAV16 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV16→partner) and Y-score (partner→TRAV16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MRPS17P5 →	+0.380	+5.548	<.001	.004	3	2
SKCM	MIR6833 →	+0.545	+3.801	<.001	.007	3	1
SKCM	MIR6817 →	+0.321	+4.495	<.001	.007	3	1
SKCM	RNU7-167P →	+0.327	+4.385	<.001	.008	3	1
SKCM	RN7SL273P →	+0.239	+3.801	.005	.009	3	1
SKCM	TRBVB →	+0.179	+4.385	.002	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Exploration

TRAV16 survival (RNA) · tumor vs normal (RNA) · all TRAV16 data types