Across TCGA patient cohorts, TRAV14DV4 mutation is significantly associated with the RNA expression of many other genes, with 80 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRAV14DV4-associated genes across cancer lineages are CSPG4P3Y, RNU6-1113P, and OR2AQ1P. Each is linked with TRAV14DV4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV14DV4-to-partner and partner-to-TRAV14DV4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV14DV4→partner) and Y-score (partner→TRAV14DV4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	CSPG4P3Y →	+0.020	+4.548	.005	.009	3	2
SKCM	RNU6-1113P →	+0.177	+4.106	<.001	.001	3	2
SKCM	OR2AQ1P →	+0.087	+3.645	<.001	.003	3	2
SKCM	RPPH1-3P →	+0.089	+4.219	<.001	.006	3	2
BLCA	SLC20A1P3 →	+0.049	+7.640	<.001	.009	3	1
SKCM	MIR6780B →	+0.409	+2.711	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 80 associations by consensus.

Exploration

TRAV14DV4 survival (RNA) · tumor vs normal (RNA) · all TRAV14DV4 data types