Across TCGA patient cohorts, TRAV12-2 mutation is significantly associated with the RNA expression of many other genes, with 797 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAV12-2-associated genes across cancer lineages are RNU6-605P, SNORD116-15, and DNAJA1P4. Each is linked with TRAV12-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAV12-2-to-partner and partner-to-TRAV12-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAV12-2→partner) and Y-score (partner→TRAV12-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-605P →	+0.380	+5.822	<.001	.003	3	2
HNSC	SNORD116-15 →	+0.543	+5.124	<.001	.008	3	2
HNSC	DNAJA1P4 →	+0.039	+5.241	.001	.007	3	2
UCEC	HGSNAT →	-0.584	-3.584	.002	.003	3	2
UCEC	RNU4-58P →	+0.304	+3.455	<.001	<.001	3	2
UCEC	RNU2-47P →	+0.115	+4.601	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 797 associations by consensus.

Exploration

TRAV12-2 survival (RNA) · tumor vs normal (RNA) · all TRAV12-2 data types