TRAPPC6A

Across TCGA patient cohorts, TRAPPC6A mutation is significantly associated with the RNA expression of many other genes, with 107 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAPPC6A-associated genes across cancer lineages are MIR383, SNORD116-10, and RNA5SP516. Each is linked with TRAPPC6A in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAPPC6A-to-partner and partner-to-TRAPPC6A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR383 grouped by TRAPPC6A-low versus TRAPPC6A-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAPPC6A→partner) and Y-score (partner→TRAPPC6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR383 →	+0.303	+7.816	<.001	.008	3	2
UCEC	SNORD116-10 →	+0.523	+4.335	<.001	.007	3	2
UCEC	RNA5SP516 →	+0.565	+4.937	<.001	<.001	3	2
UCEC	MTND1P17 →	+0.203	+4.335	.001	.007	3	2
UCEC	RPL7AP61 →	+0.100	+4.621	.001	<.001	3	2
LUSC	RNU4-54P →	+0.331	+5.882	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 107 associations by consensus.

MIR383 by TRAPPC6A expression — SKCM

Explore this box plot interactively →