TRAPPC2L

Across TCGA patient cohorts, TRAPPC2L mutation is significantly associated with the RNA expression of many other genes, with 1,235 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRAPPC2L-associated genes across cancer lineages are SMR3A, RN7SKP264, and RNU7-90P. Each is linked with TRAPPC2L in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAPPC2L-to-partner and partner-to-TRAPPC2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMR3A grouped by TRAPPC2L-low versus TRAPPC2L-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAPPC2L→partner) and Y-score (partner→TRAPPC2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	SMR3A →	+0.192	+4.497	<.001	.009	3	2
UCEC	RN7SKP264 →	+0.155	+1.936	.002	.009	3	2
UCEC	RNU7-90P →	+0.227	+2.601	<.001	.005	3	2
COAD	OR4X2 →	+0.054	+7.741	<.001	.009	3	2
HNSC	SPATA31D4 →	+0.009	+7.954	<.001	.008	3	2
BRCA	FAM236A →	+0.059	+8.057	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,235 associations by consensus.

SMR3A by TRAPPC2L expression — BLCA

Explore this box plot interactively →