TRAPPC2L

Across TCGA pan-cancer cohorts, TRAPPC2L RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated TRAPPC2L data layer compared with 5 for mutation status and 7 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TRAPPC2L RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated TRAPPC2L expression acts as an unfavorable survival marker, although some lineages such as UCEC and MESO show a favorable association.

UCEC, LIHC, and ACC are the cancer types where TRAPPC2L RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.718	0.440	<.001	74	view →
LIHC	DFS	Tertile	All	0.473	0.622	.004	29	view →
ACC	OS	Quartile	IV	0.238	0.684	.006	25	view →
MESO	OS	Tertile	All	0.508	0.289	.004	19	view →
OV	DFS	Median	IV	0.552	0.362	.013	18	view →
KIRC	DFS	Tertile	All	0.704	0.551	<.001	16	view →
SCLC	OS	Median	All	1.000	0.506	.004	16	view →
STAD	OS	Quartile	III,IV	0.633	0.409	.029	13	view →
SKCM	OS	Tertile	III,IV	0.324	0.515	.016	13	view →
KIRP	OS	Median	II,III,IV	0.902	0.737	.011	12	view →
DLBC	OS	Median	III,IV	0.272	1.000	.017	11	view →
THCA	OS	Median	II,III,IV	1.000	0.964	.024	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

TRAPPC2L–UCEC (DFS)

Open the UCEC breakdown →