TRAF7

Across TCGA cell cohorts, TRAF7 mutation is significantly associated with the RNA expression of many other genes, with 38 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TRAF7-associated genes across cancer lineages are DCD, CCT8L2, and ACTRT1. Each is linked with TRAF7 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRAF7-to-partner and partner-to-TRAF7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DCD grouped by TRAF7-low versus TRAF7-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRAF7→partner) and Y-score (partner→TRAF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	DCD →	+0.045	+5.266	<.001	.001	3	2
LUNG_NSCLC_LUAD	CCT8L2 →	+0.045	+4.371	<.001	.005	3	2
BLOOD_Lymphoma	ACTRT1 →	+0.008	+4.662	<.001	.003	3	2
BLOOD_Myeloma	ART1 →	+0.028	+3.906	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR1A2 →	+0.017	+5.266	<.001	.001	3	1
LUNG_NSCLC_LUAD	LILRA4 →	+0.052	+4.734	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

DCD by TRAF7 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →