TPTE

Across TCGA patient cohorts, TPTE RNA expression is significantly associated with the go_rna of many other GO terms, with 6,249 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TPTE-associated GO terms across cancer lineages are Methylation, Mitochondrial gene expression, and Mitotic nuclear division. Each is linked with TPTE in more than 13 cancer types. Because this analysis shows association rather than direction, both TPTE-to-partner and partner-to-TPTE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Methylation grouped by TPTE-low versus TPTE-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TPTE→partner) and Y-score (partner→TPTE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Methylation →	+0.069	+0.212	<.001	<.001	3	14
STAD	Mitochondrial gene expression →	+0.087	+0.216	<.001	<.001	3	14
STAD	Mitotic nuclear division →	+0.086	+0.175	<.001	<.001	3	14
STAD	Mitotic cell cycle checkpoint signaling →	+0.080	+0.165	<.001	<.001	3	14
STAD	Mitotic metaphase chromosome alignment →	+0.092	+0.203	<.001	<.001	3	14
STAD	Sister chromatid segregation →	+0.088	+0.217	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,249 associations by consensus.

Methylation by TPTE expression — STAD

Explore this box plot interactively →