TPRX1

Across TCGA cell cohorts, TPRX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 188 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TPRX1-associated GO terms across cancer lineages are Phosphatidylinositol phosphate biosynthetic process, Nodal signaling pathway, and Response to hydrogen peroxide. Each is linked with TPRX1 in more than 3 cancer types. Because this analysis shows association rather than direction, both TPRX1-to-partner and partner-to-TPRX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphatidylinositol phosphate biosynthetic process grouped by TPRX1-low versus TPRX1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TPRX1→partner) and Y-score (partner→TPRX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Phosphatidylinositol phosphate biosynthetic process →	+0.036	+0.018	.004	.009	3	4
LARGE_INTESTINE	Nodal signaling pathway →	+0.135	+0.003	.003	.008	3	3
SKIN	Response to hydrogen peroxide →	+0.054	+0.009	.002	.008	3	3
SKIN	Cell fate commitment →	-0.042	-0.010	.005	.008	3	3
LUNG_NSCLC_LUAD	Phosphatidylinositol biosynthetic process →	+0.034	+0.005	.002	.003	3	3
SOFT_TISSUE	Face development →	+0.104	+0.020	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 188 associations by consensus.

Phosphatidylinositol phosphate biosynthetic process by TPRX1 expression — PANCREAS

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