TPRKBP1

Across TCGA patient cohorts, TPRKBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,065 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TPRKBP1-associated GO terms across cancer lineages are Mitochondrial gene expression, tRNA metabolic process, and Mitochondrial translation. Each is linked with TPRKBP1 in more than 11 cancer types. Because this analysis shows association rather than direction, both TPRKBP1-to-partner and partner-to-TPRKBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial gene expression grouped by TPRKBP1-low versus TPRKBP1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TPRKBP1→partner) and Y-score (partner→TPRKBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial gene expression →	+0.055	+0.217	<.001	<.001	3	11
DLBC	tRNA metabolic process →	+0.057	+0.197	<.001	<.001	3	11
STAD	Mitochondrial translation →	+0.057	+0.192	<.001	<.001	3	11
ESCA	Telomere maintenance in response to DNA damage →	+0.049	+0.189	.001	<.001	3	11
ESCA	DNA-templated DNA replication →	+0.062	+0.166	.001	<.001	3	10
STAD	Transcription by RNA polymerase I →	+0.051	+0.189	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,065 associations by consensus.

Mitochondrial gene expression by TPRKBP1 expression — STAD

Explore this box plot interactively →