TPRKBP1

Across TCGA pan-cancer cohorts, TPRKBP1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TPRKBP1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where TPRKBP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TPRKBP1 is over-expressed in tumor.

LUSC and LIHC are the cancer types where TPRKBP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TPRKBP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	+0.032	.015	1	view →
LIHC	Male	All	+0.019	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

TPRKBP1–LUSC

Open the LUSC breakdown →