TPPP2

Across TCGA patient cohorts, TPPP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,515 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TPPP2-associated proteins across cancer lineages are NDRG2, WDR75_S779, and MYBBP1A_S1267. Each is linked with TPPP2 in more than 5 cancer types. Because this analysis shows association rather than direction, both TPPP2-to-partner and partner-to-TPPP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TPPP2 versus NDRG2 in BRCA, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TPPP2→partner) and Y-score (partner→TPPP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NDRG2 →	+0.654	+0.235	<.001	<.001	3	6
LUAD	WDR75_S779 →	-0.537	-0.060	<.001	<.001	3	3
LUAD	MYBBP1A_S1267 →	-0.409	-0.051	<.001	<.001	3	3
PDAC	PDCD4 →	+0.394	+0.126	<.001	.001	3	3
CCRCC	CANX →	-0.356	-0.076	.006	.009	3	3
HNSC	CEP170B_S853 →	+0.546	+0.492	.004	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,515 associations by consensus.

TPPP2 vs NDRG2 — BRCA

Explore this scatter interactively →