TPPP2

Across TCGA patient cohorts, TPPP2 protein abundance is significantly associated with the RNA expression of many other genes, with 157 significant associations in total. OV shows the largest number of these associations.

The most reproducible TPPP2-associated genes across cancer lineages are BDKRB1, GSDMD, and TGFBR1. Each is linked with TPPP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TPPP2-to-partner and partner-to-TPPP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TPPP2 versus BDKRB1 in OV, with a Pearson correlation of 0.89.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPPP2→partner) and Y-score (partner→TPPP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	BDKRB1 →	+0.484	+2.580	.009	.006	3	1
OV	GSDMD →	+1.545	+3.520	.007	.005	3	1
OV	TGFBR1 →	+0.617	+2.580	.005	.006	3	1
OV	CLEC2B →	+2.530	+3.520	.006	.005	3	1
OV	DEPDC7 →	+2.265	+3.520	.008	.005	3	1
OV	POGLUT2 →	+0.991	+2.580	.008	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 157 associations by consensus.

TPPP2 vs BDKRB1 — OV

Explore this scatter interactively →