TPPP2

Across TCGA cell cohorts, TPPP2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TPPP2-associated genes across cancer lineages are FAM47A and SHISA6. Each is linked with TPPP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TPPP2-to-partner and partner-to-TPPP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM47A grouped by TPPP2-low versus TPPP2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPPP2→partner) and Y-score (partner→TPPP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	FAM47A →	+0.026	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	SHISA6 →	+0.023	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

FAM47A by TPPP2 expression — BLOOD_Lymphoma

Explore this box plot interactively →