TPPP

Across TCGA patient cohorts, TPPP RNA expression is significantly associated with the protein abundance of many other proteins, with 21,380 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TPPP-associated proteins across cancer lineages are TPPP_S160, TPPP_T14, and TPPP_S32. Each is linked with TPPP in more than 7 cancer types. Because this analysis shows association rather than direction, both TPPP-to-partner and partner-to-TPPP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TPPP versus TPPP_S160 in CCRCC, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TPPP→partner) and Y-score (partner→TPPP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	TPPP_S160 →	+1.823	+1.505	<.001	<.001	3	8
BRCA	TPPP_T14 →	+1.445	+1.353	<.001	<.001	3	8
OV	TPPP_S32 →	+0.949	+1.285	<.001	<.001	3	7
CCRCC	NRBF2 →	-0.441	-0.849	<.001	<.001	3	5
GBM	PPIB →	-0.313	-1.228	<.001	<.001	3	5
GBM	RPS6KA5 →	+0.703	+1.695	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,380 associations by consensus.

TPPP vs TPPP_S160 — CCRCC

Explore this scatter interactively →