TPPP

Across TCGA patient cohorts, TPPP protein abundance is significantly associated with the RNA expression of many other genes, with 12,544 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TPPP-associated genes across cancer lineages are ZDHHC11B, TPPP3, and CAVIN2. Each is linked with TPPP in more than 9 cancer types. Because this analysis shows association rather than direction, both TPPP-to-partner and partner-to-TPPP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TPPP versus ZDHHC11B in LUAD, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPPP→partner) and Y-score (partner→TPPP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ZDHHC11B →	+1.495	+0.833	<.001	<.001	3	10
GBM	TPPP3 →	+1.384	+0.825	<.001	.001	3	8
CCRCC	CAVIN2 →	+1.575	+0.829	<.001	<.001	3	7
CCRCC	CLDN5 →	+0.811	+0.486	<.001	<.001	3	7
LSCC	ZDHHC11 →	+0.901	+0.478	<.001	<.001	3	7
HNSC	TGFBR3 →	+0.903	+0.567	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,544 associations by consensus.

TPPP vs ZDHHC11B — LUAD

Explore this scatter interactively →