TPD52L2

Across TCGA patient cohorts, TPD52L2 mutation is significantly associated with the RNA expression of many other genes, with 858 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TPD52L2-associated genes across cancer lineages are RNA5SP367, DUTP5, and RNU6-1064P. Each is linked with TPD52L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TPD52L2-to-partner and partner-to-TPD52L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP367 grouped by TPD52L2-low versus TPD52L2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TPD52L2→partner) and Y-score (partner→TPD52L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNA5SP367 →	+0.537	+5.010	<.001	.009	3	2
UCEC	DUTP5 →	+0.107	+2.064	.001	.002	3	2
BLCA	RNU6-1064P →	+0.478	+4.178	.005	.009	3	2
BRCA	ANKRD20A6P →	+0.153	+8.055	<.001	.007	3	1
BLCA	RN7SKP20 →	+0.149	+5.618	<.001	.002	3	1
BLCA	RNU6-1066P →	+0.428	+5.018	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 858 associations by consensus.

RNA5SP367 by TPD52L2 expression — CESC

Explore this box plot interactively →