Q-omics provides the consensus-scored DUTP5 profile across patient tissues and cancer cell-line models. DUTP5 expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in BRCA. Among the 18 cancer types available for tumor–normal comparison, DUTP5 is differentially expressed in 1, with the highest sampling consensus in UCEC. Additionally, DUTP5 RNA expression shows 5,761 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight BRCA, UCEC, and STAD as cancer lineages where DUTP5 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for DUTP5 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes DUTP5 survival associations across molecular data types. DUTP5 RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible DUTP5 RNA expression–survival associations across cancer types. High DUTP5 expression shows unfavorable associations in BRCA, CESC, ACC, THYM, ESCA and HNSC. The BRCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify BRCA as the clearest survival context for DUTP5 RNA expression.
This table summarizes DUTP5 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in UCEC for RNA.
This table ranks reproducible tumor–normal expression differences for DUTP5. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. DUTP5 shows higher tumor expression in UCEC. The UCEC box plot shows higher DUTP5 RNA expression in tumor versus normal tissue (log2 FC = +0.067, t-test p = .049).
This table shows molecular features associated with DUTP5 in patient tissues and cancer cell lines. In patient samples, DUTP5 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
