TP63

Across TCGA patient cohorts, TP63 protein abundance is significantly associated with the RNA expression of many other genes, with 11,686 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TP63-associated genes across cancer lineages are MIR205HG, MIR205, and PLXNB1. Each is linked with TP63 in more than 3 cancer types. Because this analysis shows association rather than direction, both TP63-to-partner and partner-to-TP63 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TP63 versus MIR205HG in LUAD, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TP63→partner) and Y-score (partner→TP63) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIR205HG →	+2.510	+1.360	.008	.004	3	4
PDAC	MIR205 →	+5.751	+1.998	.001	.002	3	4
LSCC	PLXNB1 →	+0.693	+0.786	<.001	<.001	3	3
LSCC	DSG4 →	+0.948	+0.749	<.001	<.001	3	3
LUAD	WNT7B →	+0.971	+1.189	.005	<.001	3	3
LSCC	MIR944 →	+2.784	+1.282	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,686 associations by consensus.

TP63 vs MIR205HG — LUAD

Explore this scatter interactively →