TP53TG5

Across TCGA cell cohorts, TP53TG5 mutation is significantly associated with the mutation status of many other genes, with 1,922 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TP53TG5-associated genes across cancer lineages are ITGA3, MAN2B1, and SGPP1. Each is linked with TP53TG5 in more than 1 cancer types. Because this analysis shows association rather than direction, both TP53TG5-to-partner and partner-to-TP53TG5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ITGA3 grouped by TP53TG5-low versus TP53TG5-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TP53TG5→partner) and Y-score (partner→TP53TG5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ITGA3 →	+4.824	+5.392	.004	.004	1	2
SKIN	MAN2B1 →	+4.824	+5.392	.004	.004	1	2
SKIN	SGPP1 →	+4.824	+5.392	.004	.004	1	2
SKIN	SLC39A6 →	+4.824	+5.392	.004	.004	1	2
SKIN	FOXK2 →	+4.824	+5.392	.004	.004	1	2
SKIN	SLC25A27 →	+5.824	+5.824	.002	.002	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,922 associations by consensus.

ITGA3 by TP53TG5 expression — SKIN

Explore this box plot interactively →