TP53RK

Across TCGA patient cohorts, TP53RK protein abundance is significantly associated with the RNA expression of many other genes, with 7,253 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TP53RK-associated genes across cancer lineages are COQ6, DNAAF2, and GON7. Each is linked with TP53RK in more than 3 cancer types. Because this analysis shows association rather than direction, both TP53RK-to-partner and partner-to-TP53RK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TP53RK versus COQ6 in OV, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TP53RK→partner) and Y-score (partner→TP53RK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	COQ6 →	+0.511	+0.457	<.001	.001	3	4
GBM	DNAAF2 →	+0.535	+0.423	<.001	<.001	3	4
LUAD	GON7 →	+0.401	+0.225	<.001	<.001	3	4
GBM	CIPC →	+0.486	+0.335	<.001	.001	3	4
OV	ZNF546 →	+0.626	+0.366	.008	.003	3	4
UCEC	CCNB2P1 →	+0.501	+0.300	.004	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,253 associations by consensus.

TP53RK vs COQ6 — OV

Explore this scatter interactively →