TP53RK

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TP53RK mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TP53RK-associated genes across cancer lineages are CD8+ Tem. Each is linked with TP53RK in more than 1 cancer types. Because this analysis shows association rather than direction, both TP53RK-to-partner and partner-to-TP53RK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ Tem grouped by TP53RK-low versus TP53RK-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TP53RK→partner) and Y-score (partner→TP53RK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCD8+ Tem →+0.006+5.481<.001.02531
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CD8+ Tem by TP53RK expression — UCEC

Box plot of CD8+ Tem in TP53RK-low vs TP53RK-high samples in UCEC.

Explore this box plot interactively →

Exploration