TP53RK

Across TCGA cell cohorts, TP53RK RNA expression is significantly associated with the go_rna of many other GO terms, with 3,736 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TP53RK-associated GO terms across cancer lineages are tRNA threonylcarbamoyladenosine metabolic process, Transcription preinitiation complex assembly, and DNA-templated transcription initiation. Each is linked with TP53RK in more than 16 cancer types. Because this analysis shows association rather than direction, both TP53RK-to-partner and partner-to-TP53RK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA threonylcarbamoyladenosine metabolic process grouped by TP53RK-low versus TP53RK-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TP53RK→partner) and Y-score (partner→TP53RK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	tRNA threonylcarbamoyladenosine metabolic process →	+0.206	+0.798	.006	<.001	3	17
SOFT_TISSUE	Transcription preinitiation complex assembly →	+0.056	+0.478	.001	.002	3	10
UPPER_AERODIGESTIVE_TRACT	DNA-templated transcription initiation →	+0.069	+0.605	<.001	<.001	3	9
SOFT_TISSUE	Protein-DNA complex organization →	+0.057	+0.749	.002	<.001	3	9
LUNG_NSCLC_LUSC	Ribosomal large subunit biogenesis →	+0.073	+0.568	.001	.004	3	9
OVARY	DNA-templated transcription elongation →	+0.076	+0.869	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,736 associations by consensus.

tRNA threonylcarbamoyladenosine metabolic process by TP53RK expression — BREAST

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