TOR1AIP1

Across TCGA patient cohorts, TOR1AIP1 mutation is significantly associated with the RNA expression of many other genes, with 2,247 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TOR1AIP1-associated genes across cancer lineages are MIR6807, RNU6-340P, and TRAJ12. Each is linked with TOR1AIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TOR1AIP1-to-partner and partner-to-TOR1AIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6807 grouped by TOR1AIP1-low versus TOR1AIP1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TOR1AIP1→partner) and Y-score (partner→TOR1AIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR6807 →	+0.477	+3.692	<.001	.009	3	2
UCEC	RNU6-340P →	+0.125	+2.635	.001	.004	3	2
UCEC	TRAJ12 →	+0.493	+1.751	<.001	.004	3	2
UCEC	RPL22P14 →	+0.091	+2.162	<.001	.002	3	2
UCEC	SFPQP1 →	+0.034	+1.653	.001	.009	3	2
UCEC	IDI1P1 →	+0.113	+1.730	.005	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,247 associations by consensus.

MIR6807 by TOR1AIP1 expression — BRCA

Explore this box plot interactively →