TOMM70

Across TCGA pan-cancer cohorts, TOMM70 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TOMM70 data layer compared with 20 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TOMM70 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TOMM70 expression acts as an unfavorable survival marker, although some lineages such as UCEC and GBM show a favorable association.

HNSC, CCRCC, and UCEC are the cancer types where TOMM70 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	All	0.270	1.000	.021	30	view →
CCRCC	DFS	Median	All	0.608	0.873	.003	9	view →
UCEC	DFS	Median	II,III,IV	0.880	0.520	.034	8	view →
LSCC	DFS	Quartile	II,III,IV	0.200	1.000	.024	8	view →
GBM	DFS	Quartile	All	0.924	0.620	.001	7	view →
LUAD	DFS	Median	All	0.534	0.860	.014	6	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

TOMM70–HNSC (DFS)

Open the HNSC breakdown →