TOMM40

Across TCGA cell cohorts, TOMM40 protein abundance is significantly associated with the RNA expression of many other genes, with 3,673 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TOMM40-associated genes across cancer lineages are EBF4, EIF3E, and GRPEL1. Each is linked with TOMM40 in more than 4 cancer types. Because this analysis shows association rather than direction, both TOMM40-to-partner and partner-to-TOMM40 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TOMM40 versus EBF4 in KIDNEY, with a Pearson correlation of 0.93.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TOMM40→partner) and Y-score (partner→TOMM40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	EBF4 →	+2.804	+1.872	.006	<.001	3	5
LUNG_SCLC	EIF3E →	-1.041	-0.846	.001	.002	3	4
LUNG_SCLC	GRPEL1 →	-0.868	-0.830	.002	<.001	3	4
LUNG_SCLC	WNT7B →	+1.783	+1.063	<.001	.002	3	4
OVARY	EPB41L2 →	-1.359	-1.683	.005	.009	3	4
BLOOD_Leukemia	RIMS3 →	+2.024	+1.179	.006	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,673 associations by consensus.

TOMM40 vs EBF4 — KIDNEY

Explore this scatter interactively →