TNNC1

Across TCGA patient cohorts, TNNC1 mutation is significantly associated with the RNA expression of many other genes, with 108 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TNNC1-associated genes across cancer lineages are RN7SL754P, KSR1P1, and RN7SL316P. Each is linked with TNNC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNNC1-to-partner and partner-to-TNNC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL754P grouped by TNNC1-low versus TNNC1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNNC1→partner) and Y-score (partner→TNNC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL754P →	+0.431	+4.223	<.001	.003	3	2
SKCM	KSR1P1 →	+0.558	+2.838	<.001	.004	3	2
SKCM	RN7SL316P →	+0.315	+2.915	.003	.007	3	2
COAD	RNA5SP409 →	+0.345	+7.741	<.001	.009	3	1
BLCA	FGF7P4 →	+0.114	+7.640	<.001	.009	3	1
BLCA	MIR1231 →	+0.318	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 108 associations by consensus.

RN7SL754P by TNNC1 expression — UCEC

Explore this box plot interactively →