TNNC1

Across TCGA cell cohorts, TNNC1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TNNC1-associated genes across cancer lineages are BPIFB6 and KRTAP5-4. Each is linked with TNNC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNNC1-to-partner and partner-to-TNNC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BPIFB6 grouped by TNNC1-low versus TNNC1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNNC1→partner) and Y-score (partner→TNNC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	BPIFB6 →	+0.047	+4.969	<.001	.003	3	1
SKIN	KRTAP5-4 →	+0.101	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

BPIFB6 by TNNC1 expression — BLOOD_Leukemia

Explore this box plot interactively →