TNIP1

Across TCGA cell cohorts, TNIP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,644 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TNIP1-associated GO terms across cancer lineages are Positive regulation of protein deubiquitination, Negative regulation of immune response, and Positive regulation of canonical NF-kappaB signal transduction. Each is linked with TNIP1 in more than 16 cancer types. Because this analysis shows association rather than direction, both TNIP1-to-partner and partner-to-TNIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein deubiquitination grouped by TNIP1-low versus TNIP1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNIP1→partner) and Y-score (partner→TNIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of protein deubiquitination →	+0.184	+1.281	<.001	<.001	3	17
PANCREAS	Negative regulation of immune response →	+0.101	+1.193	<.001	<.001	3	17
PANCREAS	Positive regulation of canonical NF-kappaB signal transduction →	+0.068	+1.273	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Antigen processing and presentation of endogenous antigen →	+0.258	+1.415	.001	<.001	2	17
LUNG_SCLC	Antigen processing and presentation of endogenous peptide antigen via MHC class I →	+0.257	+1.213	<.001	<.001	3	16
LUNG_SCLC	Antigen processing and presentation of peptide antigen via MHC class I →	+0.215	+1.269	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,644 associations by consensus.

Positive regulation of protein deubiquitination by TNIP1 expression — OESOPHAGUS

Explore this box plot interactively →