TNFSF4

Across TCGA patient cohorts, TNFSF4 mutation is significantly associated with the RNA expression of many other genes, with 997 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TNFSF4-associated genes across cancer lineages are UBE2CP4, LINC00690, and RNU7-56P. Each is linked with TNFSF4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFSF4-to-partner and partner-to-TNFSF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBE2CP4 grouped by TNFSF4-low versus TNFSF4-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF4→partner) and Y-score (partner→TNFSF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	UBE2CP4 →	+0.144	+5.033	<.001	.009	3	2
LUAD	LINC00690 →	+0.068	+3.962	<.001	.005	3	2
BRCA	RNU7-56P →	+0.909	+5.148	<.001	.008	3	2
UCEC	SPATA12 →	+0.436	+2.627	.002	.006	3	2
UCEC	RNU4-4P →	+0.361	+2.345	.003	.007	3	2
UCEC	UBAP1L →	+0.450	+3.387	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 997 associations by consensus.

UBE2CP4 by TNFSF4 expression — LIHC

Explore this box plot interactively →