TNFSF18

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TNFSF18 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TNFSF18-associated genes across cancer lineages are GMP, Adipocytes, and iDC. Each is linked with TNFSF18 in more than 2 cancer types. Because this analysis shows association rather than direction, both TNFSF18-to-partner and partner-to-TNFSF18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by TNFSF18-low versus TNFSF18-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF18→partner) and Y-score (partner→TNFSF18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMGMP →+0.060+1.958<.001.02933
UCECAdipocytes →+0.020+3.529.043.00431
UCECiDC →-0.196-3.000.032.03621
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

GMP by TNFSF18 expression — SKCM

Box plot of GMP in TNFSF18-low vs TNFSF18-high samples in SKCM.

Explore this box plot interactively →

Exploration