TNFSF12-TNFSF13

Across TCGA patient cohorts, TNFSF12-TNFSF13 mutation is significantly associated with the RNA expression of many other genes, with 53 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TNFSF12-TNFSF13-associated genes across cancer lineages are LINC01072, LINC02559, and SUMO2P5. Each is linked with TNFSF12-TNFSF13 in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFSF12-TNFSF13-to-partner and partner-to-TNFSF12-TNFSF13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01072 grouped by TNFSF12-TNFSF13-low versus TNFSF12-TNFSF13-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFSF12-TNFSF13→partner) and Y-score (partner→TNFSF12-TNFSF13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC01072 →	+0.180	+5.345	<.001	.001	3	2
CESC	LINC02559 →	+1.025	+5.342	<.001	.002	3	1
CESC	SUMO2P5 →	+0.122	+5.837	<.001	.001	3	1
CESC	MIR4510 →	+0.300	+5.342	<.001	.002	3	1
CESC	MIR5580 →	+0.638	+5.144	<.001	.003	3	1
CESC	PRAMEF28P →	+0.101	+4.969	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

LINC01072 by TNFSF12-TNFSF13 expression — CESC

Explore this box plot interactively →