TNFRSF10C

Across TCGA cell cohorts, TNFRSF10C RNA expression is significantly associated with the go_rna of many other GO terms, with 2,778 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TNFRSF10C-associated GO terms across cancer lineages are Regulation of intracellular protein transport, Regulation of CD4-positive, alpha-beta T cell differentiation, and Positive regulation of intracellular transport. Each is linked with TNFRSF10C in more than 7 cancer types. Because this analysis shows association rather than direction, both TNFRSF10C-to-partner and partner-to-TNFRSF10C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intracellular protein transport grouped by TNFRSF10C-low versus TNFRSF10C-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF10C→partner) and Y-score (partner→TNFRSF10C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of intracellular protein transport →	+0.074	+0.635	.003	.006	3	8
PANCREAS	Regulation of CD4-positive, alpha-beta T cell differentiation →	+0.087	+1.900	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular transport →	+0.054	+0.174	.001	.001	2	8
PANCREAS	Membrane protein intracellular domain proteolysis →	+0.140	+1.238	<.001	<.001	3	7
PANCREAS	Membrane biogenesis →	+0.086	+0.975	<.001	.009	2	8
LUNG_NSCLC_LUSC	Regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains →	+0.045	+1.049	.008	.008	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,778 associations by consensus.

Regulation of intracellular protein transport by TNFRSF10C expression — URINARY_TRACT

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