TNFRSF10C

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TNFRSF10C mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TNFRSF10C-associated genes across cancer lineages are FERD3L. Each is linked with TNFRSF10C in more than 1 cancer types. Because this analysis shows association rather than direction, both TNFRSF10C-to-partner and partner-to-TNFRSF10C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FERD3L grouped by TNFRSF10C-low versus TNFRSF10C-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF10C→partner) and Y-score (partner→TNFRSF10C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEFERD3L →+0.079+4.977<.001.00731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

FERD3L by TNFRSF10C expression — LARGE_INTESTINE

Box plot of FERD3L in TNFRSF10C-low vs TNFRSF10C-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration