TNFRSF10A

Across TCGA patient cohorts, TNFRSF10A RNA expression is significantly associated with the protein abundance of many other proteins, with 14,425 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TNFRSF10A-associated proteins across cancer lineages are XPO7, CHMP7, and PPP2CB. Each is linked with TNFRSF10A in more than 7 cancer types. Because this analysis shows association rather than direction, both TNFRSF10A-to-partner and partner-to-TNFRSF10A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFRSF10A versus XPO7 in BRCA, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF10A→partner) and Y-score (partner→TNFRSF10A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	XPO7 →	+0.429	+0.647	<.001	<.001	3	8
OV	CHMP7 →	+0.325	+1.060	.002	<.001	3	8
OV	PPP2CB →	+0.518	+0.804	.001	.003	3	7
OV	CCAR2 →	+0.274	+0.783	<.001	<.001	3	7
LUAD	SH2D4A →	+0.503	+0.573	<.001	<.001	3	6
UCEC	KCTD9 →	+0.363	+1.030	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,425 associations by consensus.

TNFRSF10A vs XPO7 — BRCA

Explore this scatter interactively →