TNFRSF10A

Across TCGA patient cohorts, TNFRSF10A protein abundance is significantly associated with the RNA expression of many other genes, with 5,603 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TNFRSF10A-associated genes across cancer lineages are GGA2, CTSH, and RPS10. Each is linked with TNFRSF10A in more than 2 cancer types. Because this analysis shows association rather than direction, both TNFRSF10A-to-partner and partner-to-TNFRSF10A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TNFRSF10A versus GGA2 in CCRCC, with a Pearson correlation of -0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TNFRSF10A→partner) and Y-score (partner→TNFRSF10A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	GGA2 →	-0.612	-0.971	<.001	<.001	3	3
LUAD	CTSH →	-1.007	-0.631	<.001	<.001	3	3
HNSC	RPS10 →	+0.741	+0.630	.006	.002	3	3
BRCA	AOC3 →	-1.012	-0.584	<.001	<.001	3	3
BRCA	DOCK10 →	-1.015	-0.760	<.001	<.001	3	3
BRCA	PLXNC1 →	-0.918	-0.608	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,603 associations by consensus.

TNFRSF10A vs GGA2 — CCRCC

Explore this scatter interactively →